A Longitudinal Renal Health Outcome for Clinical Trials in Acute Kidney Injury?

I applaud your efforts John. I’d like to see the definition of the new ordinal scale. Your background information mentions changes in SCr. There are fundamental problems with this: * SCr is not a variable that is properly transformed to be used in a subtraction * Any outcome variable needs to have a definition that is independent of the time gap between SCr measurements and should be based on renal function at the time the outcome is assessed * If only SCr were needed, it could be the outcome scale, with no binning, and dialysis or death added to the top of the scale * A few random ideas related to combining multiple measurements into a single outcome scale are here