A Longitudinal Renal Health Outcome for Clinical Trials in Acute Kidney Injury?

Thank you Frank, I am working with John on this and come from a clinical background too. Based on your comments, could a step forward be to test a longitudinal ordinal SCr / dialysis / death outcome against our proposed scale (urea thresholds, urine output, eGFR, K/BE thresholds, AKI etc)? I would have to research how to assess the performance of these models against each other.