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  "path": "/t/a-longitudinal-renal-health-outcome-for-clinical-trials-in-acute-kidney-injury/28750#post_6",
  "publishedAt": "2026-05-19T21:34:49.000Z",
  "site": "https://discourse.datamethods.org",
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  "textContent": "I applaud your efforts John.\n\nI’d like to see the definition of the new ordinal scale.\n\nYour background information mentions changes in SCr. There are fundamental problems with this:\n\n  * SCr is not a variable that is properly transformed to be used in a subtraction\n  * Any outcome variable needs to have a definition that is independent of the time gap between SCr measurements and should be based on renal function at the time the outcome is assessed\n  * If only SCr were needed, it could be the outcome scale, with no binning, and dialysis or death added to the top of the scale\n  * A few random ideas related to combining multiple measurements into a single outcome scale are here\n\n",
  "title": "A Longitudinal Renal Health Outcome for Clinical Trials in Acute Kidney Injury?"
}