Statin-related side effects: the recent Lancet publication is biased toward false-negatives

f2harrell:

I’ve always thought that absolute risks should be emphasized much more.

Providing absolute risks differences would help contextualize AE info. Another form of contextualization (not sure a Fundamentalist Bayesian would agree tho’) would be substantive knowledge about mechanism : is this rare AE well-understood, or is it (so far) just a data artifact lacking a plausible mechanistic explanation?