Ultrafast MRI uncovers brain signal direction: New scan may help decode autism, Alzheimer's and hallucinations

Researchers at the Champalimaud Foundation in Lisbon have for the first time managed to identify with an imaging technique whether nervous impulses in the brain of rats are flowing in a "bottom-up" (feedforward), carrying information about visual input, or a "top-down" (feedback) direction, carrying information about expectations or predictions on a given task or about the perception of the world around us. Their results, published in Nature Communications, could have important implications for understanding changes in the brains of people with hallucinations, Alzheimer's, schizophrenia, autism, and other conditions.