Single dose of a psychedelic drug can rapidly reduce depressive symptoms, clinical trial suggests

A single dose of the psychedelic drug dimethyltryptamine (DMT), given with psychological support, rapidly reduced depressive symptoms in 34 adults with major depressive disorder, according to a clinical trial published in Nature Medicine. The improvements, which continued over the ensuing two weeks, suggest that this short-acting treatment could be a more practical therapy compared with other longer-acting psychedelic therapies.