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  "path": "/news/2026-02-dose-psychedelic-drug-rapidly-depressive.html",
  "publishedAt": "2026-02-17T10:20:03.000Z",
  "site": "https://medicalxpress.com",
  "tags": [
    "Psychology & Psychiatry"
  ],
  "textContent": "A single dose of the psychedelic drug dimethyltryptamine (DMT), given with psychological support, rapidly reduced depressive symptoms in 34 adults with major depressive disorder, according to a clinical trial published in Nature Medicine. The improvements, which continued over the ensuing two weeks, suggest that this short-acting treatment could be a more practical therapy compared with other longer-acting psychedelic therapies.",
  "title": "Single dose of a psychedelic drug can rapidly reduce depressive symptoms, clinical trial suggests"
}