S-triazine derivatives containing at least two silated p-aminobenzalmalonate groups, sunscreen compositions containing these derivatives as well as the use of the derivatives

DRIVE August 31, 2005
Source
Silanic para-aminobenzalmalonate substituted S-triazine compounds (I) are new. Silanic para-aminobenzalmalonate substituted S-triazine compounds of formula (I) are new. R 1-R 3optionally saturated 1-10C alkyl (optionally substituted with one or more halo), phenyl or CH 3; p : 0-1; A : H, optionally saturated 1-8C alkyl, phenyl or Si(CH 3) 3, provided that when A is Si(CH 3) 3, then p is 0; W 1optionally saturated 1-8C alkylene (optionally substituted by hydroxyl group); Z : (C=O)OR 4, -(C=O)R 5, -(C=O)NR 6R 7, -SO 2R 8, CN or (C=O)YCHA(W 1) pSiR 1R 2R 3; R 4H or an optionally saturated 1-20C alkyl radical; R 5, R 81-20C alkyl or 6-12C aryl; R 6, R 7H or 1-20C alkyl; Y : O or NR 7; and B 1chromophoric group of para-aminobenzalmalonate, aminobenzimidazole, benzimidazole, aminobenzoate, aminosalicylate, anthranilate, aminobenzylidenecamphor, aminobenzotriazole, aminobenzoxazole or para aminophenylbenzoxazole substituents, provided that B 1can also be 1-20C aminoalkyl or 6-20C aryl radical which can be optionally substituted by alkyl, hydroxyl and/or alkoxy. Independent claims are also included for: (1) a topically applicable UV-photoprotective cosmetic/dermatological composition (A) comprising (I) and a cosmetic/dermatological vehicle; (2) a regime or regimen for the UV-photoprotection of the skin against the damaging effects of UV-radiation and for controlling the variation in the color of the skin due to UV-radiation comprising topically applying (A); and (3) a synthetic polymer or glass comprising a photostabilizing amount of (I). [Image] ACTIVITY : Dermatological. MECHANISM OF ACTION : None given.

Discussion in the ATmosphere

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