Wipr 2 uses Apple's new 'URL Filters'

The DNS filter you’re using is blocking the domains Apple uses for Private Relay, OHTTP, etc. They’re for hiding your IP address, you should probably figure out how to allow those or change what DNS you’re using. I assume it’s just blocking those domains because they’re Apple domains and they don’t really consider what the purpose is of the domains they’re blocking. You don’t need the DNS blocker on your iPhone with this enabled, this is going to be more effective and more private.