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MLB First Pitch Picks Today: Best Bets (May 7th) | MLB EDGE

edgely.bet May 7, 2026
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MLB Matchup Preview: First Pitch Plays

Thursday baseball is here, and while the slate might be small, there's plenty of excitement packed into the first pitch plays. Whether you're a seasoned bettor or just love the game, let's dive into the breakdowns for each matchup and see where we might find some value.

📍Note: always verify starting lineups as this blog is written before most lineups are confirmed using projected starting pitchers, lineups, and batting orders.

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New to this market? Check out our Complete Guide to MLB First Pitch Betting Strategy to understand the data and "fair odds" calculations we use for these daily picks.

Twins @ Nationals: Byron Buxton vs. Jake Irvin

Projected Outcome: In play with an 18.4% chance (fair odds +445)

  • Jake Irvin : Throws in the zone 62.5% of the time, swings generated 27.5%, balls in play 10.0%
  • Byron Buxton : Swings 53.8% of the time, puts in play 22.7%

Twins @ Nationals: James Wood vs. Simeon Woods Richardson

Projected Outcome: In play with a 14.1% chance (fair odds +607)

* Woods Richardson: Zone 62.1%, swings 20.7%, in play 13.8%
* Wood: Swings 35.1%, in play 15.6%

Guardians @ Royals: Steven Kwan vs. Seth Lugo

Projected Outcome: Strike with an 80.2% chance (fair odds -405)

  • Seth Lugo : Throws in the zone 82.4% of the time, balls in play 20.6%
  • Steven Kwan : Swings 3.6% of the time, puts in play 1.6%

Guardians @ Royals: Maikel Garcia vs. Slade Cecconi

Projected Outcome: In play with a 13.9% chance (fair odds +620)

* Cecconi: Zone 58.1%, swings 25.8%, in play 9.7%
* Garcia: Swings 30.4%, in play 17.9%

Reds @ Cubs: Dane Myers vs. Shota Imanaga

Projected Outcome: Ball with a 51.5% chance (fair odds -106)

  • Shota Imanaga : Throws a first pitch ball 51.5% of the time

Reds @ Cubs: Nico Hoerner vs. Rhett Lowder

Projected Outcome: Ball with an 85.7% chance (fair odds -600)

* Lowder: Throws a first pitch ball 85.7% of the time

Mets @ Rockies: Bo Bichette vs. Jose Quintana

Projected Outcome: In play with a 16.2% chance (fair odds +519)

  • Jose Quintana : Throws in the zone 58.1% of the time, swings generated 29.0%, balls in play 9.7%
  • Bo Bichette : Swings 39.8% of the time, puts in play 21.5%

Pirates @ D-backs: Oneil Cruz vs. Zac Gallen

Projected Outcome: Ball with a 47.5% chance (fair odds +111)

  • Zac Gallen : Throws a first pitch ball 47.5% of the time

Orioles @ Marlins: Gunnar Henderson vs. Max Meyer

Projected Outcome: Ball with a 47.4% chance (fair odds +111)

  • Max Meyer : Throws a first pitch ball 47.4% of the time

Cardinals @ Padres: Ramon Laureano vs. Matthew Liberatore

Projected Outcome: Strike with a 75.0% chance (fair odds -300)

* Liberatore: Zone 75.0%, in play 13.9%
* Laureano: Swings 17.4%, in play 0.0%

Conclusion

These first pitch plays offer intriguing insights into how each matchup might unfold. Keep an eye on the pitchers and their tendencies, as they often hold the key to unlocking value in these bets. Whether you're looking to place a bet or just enjoy the game, Thursday's slate is set to deliver some interesting moments right from the start.

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