Melatonin — the Missing Link Between Sleep Deprivation and Immune Dysregulation

STORY AT-A-GLANCE A 2025 review of 50 studies found that sleep deprivation lowers melatonin, which directly increases inflammatory signals and weakens immune cell performance When melatonin drops, your immune cells lose energy, struggle to coordinate their defense tasks and become less effective at fighting infections Chronic sleep disruption raises stress hormones like cortisol, shifts immune […]