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Butyrate and GLP-1 — Dual Messengers Linking Gut Health to Brain Health

did:plc:yhmwewfk3g3hhkrw2gf4ypna March 19, 2026
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STORY AT-A-GLANCE Gut bacteria ferment fiber into butyrate, which triggers L-cells to release GLP-1 — the same hormone targeted by weight loss drugs When your gut produces enough butyrate, natural GLP-1 secretion works properly, supporting appetite control, insulin sensitivity, and weight regulation Butyrate also crosses the blood-brain barrier to reduce neuroinflammation, boost BDNF (a brain […]

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