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  "path": "/t/biomarker-ratios/28716#post_1",
  "publishedAt": "2026-04-22T11:09:02.000Z",
  "site": "https://discourse.datamethods.org",
  "textContent": "In veterinary medicine I frequently see papers that use biomarkers such as neutrophil:lymphocyte ratio for diagnostic or prognostic purposes. I recall reading that there are statistical problems with this approach. One I can see is that it actually loses information due to turning two continuous variables into a single dichotomized variable. Are there any other concerns that I can point out to my colleagues?",
  "title": "Biomarker ratios"
}