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  "path": "/t/thinking-clearly-about-association-studies-risk-factors-and-causal-salad-included/28679#post_17",
  "publishedAt": "2026-04-03T08:24:24.000Z",
  "site": "https://discourse.datamethods.org",
  "tags": [
    "LWW",
    "Where Do Target Trials Come From? Specifying the Protocol... : Epidemiology"
  ],
  "textContent": "Check out the new paper from Hernan et al. where he questions some of the above:\n\nLWW\n\n### Where Do Target Trials Come From? Specifying the Protocol... : Epidemiology\n\ness to. When using preexisting observational databases, the target trial protocol typically needs to be iteratively developed as investigators learn about the data. Here we examine the process by which investigators adapt their original causal...",
  "title": "Thinking Clearly about Association Studies (Risk Factors and Causal Salad included)"
}