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  "path": "/t/generalizability-vs-transportability-in-trials/28551?page=3#post_51",
  "publishedAt": "2026-03-01T13:08:06.000Z",
  "site": "https://discourse.datamethods.org",
  "textContent": "llynn:\n\n> A randomized trial estimates an average treatment effect, not the effect for any specific patient.\n\nThat makes sense, and I’ll add that a randomized trial provides the best available estimate of the likely benefit of therapy for an individual patient. That is, until more covariates come along that should have been included in the covariate adjusted treatment comparison. For a normally-distributed continuous outcome Y, the mean Y in a group of similar patients is the best available estimate of the outcome for an individual in the group, if low mean squared error is your goal.",
  "title": "Generalizability vs. Transportability in Trials"
}