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  "path": "/news/2026-06-evidence-sugar-substitutes-disrupt-gut.html",
  "publishedAt": "2026-06-30T11:20:15.000Z",
  "site": "https://medicalxpress.com",
  "textContent": "Since the first introduction of saccharin, an array of artificial and other non-nutritive (i.e., low-calorie or calorie-free) sweeteners have become ubiquitous in the U.S. food supply. However, a growing body of research suggests that these compounds are not inert in the body and may be disrupting metabolism.",
  "title": "Growing evidence shows sugar substitutes disrupt gut health and metabolism"
}