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  "path": "/news/2026-06-immune-cellfibroblast-crosstalk-key-trigger.html",
  "publishedAt": "2026-06-24T18:40:02.000Z",
  "site": "https://medicalxpress.com",
  "textContent": "In autoimmune disorders, immune cells targeting \"self\" proteins are mistakenly activated, resulting in abnormal expansion and responsiveness. These disorders are known to reduce patients' quality of life over a prolonged period. This can be attributed to CD4+ T cells, which play a key role in inducing persistent inflammation, recruiting other immune cells, including antibody-producing B cells, and inflicting tissue damage.",
  "title": "Immune cell–fibroblast crosstalk may be the key trigger of autoimmune diseases"
}