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  "path": "/news/2026-06-psilocybin-combined-psychotherapy-antidepressant-effects.html",
  "publishedAt": "2026-06-17T12:20:04.000Z",
  "site": "https://medicalxpress.com",
  "textContent": "Psilocybin combined with psychotherapy can lead to long-term improvements in depressive symptoms in people with treatment-resistant depression. This has been shown by a recently published long-term follow-up study conducted by the Central Institute of Mental Health (CIMH), Charité–Universitätsmedizin Berlin and the MIND Foundation. The antidepressant effects persisted for up to 12 months.",
  "title": "Psilocybin combined with psychotherapy demonstrates antidepressant effects over a 12-month period"
}