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  "path": "/news/2026-06-genetic-rare-skin-condition-therapeutic.html",
  "publishedAt": "2026-06-15T17:00:07.000Z",
  "site": "https://medicalxpress.com",
  "textContent": "An international team of researchers report in the journal Nature Immunology that a mutation in the gene OTULIN causes pediatric-onset pyoderma gangrenosum, characterized by recurrent ulcerating skin sores. They classify the condition as a new inborn error of immunity (IEI)—one of a group of more than 500 genetic disorders that impair the development or function of the immune system.",
  "title": "Genetic cause for rare skin condition points to new therapeutic option"
}