Behavioral modifications like goal setting could lead to greater weight loss on tirzepatide

One of the largest real-world studies of people taking GLP-1 medications found women, those without pre-existing conditions such as type 2 diabetes and high blood pressure, and behavioral factors such as previously setting a weight goal were the best predictors of total weight loss, according to a study presented at ENDO 2026, the Endocrine Society's annual meeting in Chicago.