Metal-free carbon monoxide prodrugs may help prevent cancer's deadly spread

A carefully designed metal-free carbon monoxide prodrug—an inactive compound that is converted into its active form in the body—may help prevent some of the deadliest forms of cancer from spreading, according to researchers at Weill Cornell Medicine. Their recent preclinical study, published in Advanced Science, offers a new strategy to potentially reduce the recurrence of pancreatic and triple-negative breast cancer in patients who initially respond to treatment.