Early Rett syndrome clues emerge as 12 genes shift before symptoms appear

To better understand what drives the emergence of symptoms in Rett syndrome, researchers at Baylor College of Medicine and the Duncan Neurological Research Institute (Duncan NRI) at Texas Children's Hospital took a closer look at brain cells in mice modeling Rett syndrome before symptoms appeared. They identified a set of dysfunctional genes and specific cell types that are vulnerable early to genetic changes. The study appears in Science Advances.