Potentially reversible ALS mechanism changes understanding of the disease

In Canada, between 3,000 and 4,000 people are living with amyotrophic lateral sclerosis (ALS), a disease that remains incurable. ALS is best known for the degeneration of motor neurons, which are responsible for controlling movement. Their progressive loss, particularly in the motor cortex and spinal cord, leads to rapid paralysis, with a life expectancy of 2 to 5 years after diagnosis.