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  "path": "/news/2026-05-duration-depression-severely-disease-brain.html",
  "publishedAt": "2026-05-21T15:00:01.000Z",
  "site": "https://medicalxpress.com",
  "textContent": "Depression affects about 5.8% of the Brazilian population and presents a wide range of symptoms, intensities, and durations. A study published in Scientific Reports involving patients with major depressive disorder demonstrated that the severity of symptoms, as measured by the Hamilton Depression Scale, and the length of time a person remains depressed (chronicity), are both associated with changes in brain function.",
  "title": "Duration of depression may influence how severely the disease alters the brain"
}