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  "path": "/news/2026-05-chemotherapy-backfire-immune-shift-tumor.html",
  "publishedAt": "2026-05-18T18:20:06.000Z",
  "site": "https://medicalxpress.com",
  "textContent": "Chemotherapy can be life-saving for many patients, but not all tumors respond—and some that do, may eventually become resistant. Investigators at Houston Methodist have identified a possible explanation for this resistance, offering new insight into why certain cancers evade treatment.",
  "title": "How chemotherapy can backfire: An immune shift tied to tumor resistance and poorer outcomes"
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