Chronic traumatic encephalopathy symptom checklist misses the mark in 75% of cases, autopsies show

Most people who met proposed clinical criteria meant to identify chronic traumatic encephalopathy (CTE) during life did not show hallmark brain changes of the disease at autopsy. The findings raise concerns that widespread clinical adoption of these criteria could lead to misdiagnosis and unintended mental health consequences for people at higher risk, including athletes and military veterans.