{
  "$type": "site.standard.document",
  "bskyPostRef": {
    "cid": "bafyreibxbzn6igk3nvrjpzzdykmwxegbf3e3x74fgdjbocqxjmbobtg2vq",
    "uri": "at://did:plc:pmmp7irwts7faw56jdxk3idc/app.bsky.feed.post/3mlqtwz734v52"
  },
  "coverImage": {
    "$type": "blob",
    "ref": {
      "$link": "bafkreiemepgnvqckubhu3nnnpdg7yte6xxevhwetliowfpp7qa2n7ixwni"
    },
    "mimeType": "image/jpeg",
    "size": 237592
  },
  "path": "/news/2026-05-future-cancer-therapy-immunity-dna.html",
  "publishedAt": "2026-05-13T13:03:03.000Z",
  "site": "https://medicalxpress.com",
  "textContent": "Researchers have identified a pathway that triggers an immune response in cells with defective DNA repair. In particular, the authors of a new paper demonstrated how the downregulation of AUF1 impairs DNA repair, followed by activation of the immune response due to the presence of R-loops in the cytoplasm. This represents an important finding for the development of new therapeutic strategies aimed at modulating the immune response upon DNA damage.",
  "title": "Future cancer therapy could use immunity to clean up damaged DNA by modulating AUF1"
}