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  "path": "/news/2026-05-oral-small-molecule-glp-drugs.html",
  "publishedAt": "2026-05-06T12:20:08.000Z",
  "site": "https://medicalxpress.com",
  "textContent": "A study has found that an emerging class of GLP-1 weight-loss drugs suppresses eating for pleasure, or hedonic feeding, in mice by modulating a reward circuit deep within the brain. This newly charted pathway—separate from previously described mechanisms that broadly affect appetite—could be an avenue by which GLP-1s treat other dysfunctions in reward processing, such as substance use disorder.",
  "title": "Oral small-molecule GLP-1 drugs penetrate deep into the brain to suppress cravings"
}