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  "path": "/news/2026-04-deprivation-disrupts-gut-microbiota-worsening.html",
  "publishedAt": "2026-04-16T16:00:11.000Z",
  "site": "https://medicalxpress.com",
  "textContent": "Sleep deprivation has long been known to weaken the immune system. Now UF Health Cancer Institute researchers have made a startling discovery: The gut microbiota drives changes to the immune system caused by chronic sleep loss. These changes promote cancer progression, disrupt the circadian rhythm, and weaken the effectiveness of chemotherapy.",
  "title": "Sleep deprivation disrupts gut microbiota, worsening colorectal cancer outcomes"
}