How the brain's blood vessel network follows a three-stage blueprint from birth to adulthood

Researchers from the Paris Brain Institute and Sainte-Justine University Hospital in Montreal have, for the first time, revealed the key stages of vascular development in the brain, from birth through adulthood. Using a 3D digital atlas called Lambada, they show that vascularization does not progress continuously, but instead unfolds in three distinct phases, closely linked to the maturation of neural circuits. These findings are published in Cell.