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  "path": "/news/2026-04-reprogramming-regulatory-cells-immunotherapy-pancreatic.html",
  "publishedAt": "2026-04-10T19:00:03.000Z",
  "site": "https://medicalxpress.com",
  "textContent": "Researchers at Oregon Health & Science University have uncovered a key reason why immunotherapy has largely failed in pancreatic cancer—and identified a promising strategy to overcome that resistance. The study, published in the journal Immunity, shows that pancreatic tumors actively reshape their immune environment by co-opting regulatory immune cells that normally shut down tumor-killing cells. By reprogramming those cells, the research reveals a potential pathway to make immunotherapy effective against one of the deadliest and most treatment-resistant cancers.",
  "title": "Reprogramming regulatory T cells could help immunotherapy work in pancreatic cancer"
}