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  "path": "/news/2026-04-mechanisms-tumor-suppressor-bap1-highlight.html",
  "publishedAt": "2026-04-02T19:40:03.000Z",
  "site": "https://medicalxpress.com",
  "textContent": "A team of scientists led by the National Cancer Center Singapore (NCCS) and Duke-NUS Medical School (Duke-NUS) has found a new approach for treating some of the world's most aggressive cancers associated with BAP1 mutations. Their research, published in the journal Science Translational Medicine on 1 April 2026, uncovers how BAP1 functions at the molecular level and presents a novel therapeutic strategy to slow the progression of mesothelioma, uveal melanoma, cholangiocarcinoma, and clear cell renal cell carcinoma harboring BAP1 mutations.",
  "title": "Mechanisms behind tumor suppressor BAP1 highlight new treatment strategies for aggressive cancers"
}