Leukemia study restores silenced gene in mice. Could it point to new treatments for humans?

A key cancer-fighting gene in leukemia is switched off—not broken—and scientists from The Jackson Laboratory (JAX) have found a way to switch it back on. In a study published in Science Translational Medicine, the team reveals not only a potential new way to treat acute myeloid leukemia (AML) without harsh chemotherapy, but also a promising strategy to study more gene-silencing mechanisms in other diseases.