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  "path": "/news/2026-04-therapeutic-nasally-dna-vaccine-fuses.html",
  "publishedAt": "2026-04-01T16:40:07.000Z",
  "site": "https://medicalxpress.com",
  "textContent": "In a paper published in the Journal of Clinical Investigation, a research team at Johns Hopkins Medicine and the Johns Hopkins Bloomberg School of Public Health reports developing a therapeutic intranasal (nose-delivered) DNA vaccine against tuberculosis (TB) that fuses two genes with the goal of directing the immune system to fight drug-tolerant bacterial \"persisters\" that can survive prolonged antibiotic therapy and contribute to disease relapse.",
  "title": "Therapeutic, nasally delivered DNA vaccine fuses two genes to help fight tuberculosis"
}