Scientists discover new genetic disease that causes premature aging and cognitive deficits

Scientists at Sanford Burnham Prebys Medical Discovery Institute and an international team of collaborators have defined a new genetic disease marked by premature aging and deficits in brain function. The researchers have published results in Nature Communications describing the first known project to combine genome sequencing with cellular reprogramming to identify which gene mutation is at fault and study how it causes the symptoms observed in patients suffering from this newly discovered disease.