A new glioblastoma target: Blocking CD47 protein's tumor-driving role may slow growth

Australian researchers have uncovered a critical mechanism driving the growth and spread of glioblastoma—one of the most aggressive and lethal forms of brain cancer—potentially paving the way for more effective treatments. In a study led by Adelaide University scientists from the Centre for Cancer Biology (CCB), researchers have identified a previously unrecognized role for a protein called CD47 in promoting tumor progression, independent of its known function in helping cancer evade the immune system. The work appears in Proceedings of the National Academy of Sciences.