Why some breast cancers spread faster: Jagged1 may trigger a tissue-stiffening feedback loop

A research group led by Professor Cecilia Sahlgren at Åbo Akademi University (Finland) and the InFLAMES Research Flagship has identified a new mechanism directing the adverse remodeling of tumor tissue during breast cancer progression. This discovery could offer new treatment opportunities against aggressive forms of breast cancer that currently lack targeted therapy options. The findings are published in the journal Science Advances.