Osteoporosis drugs may cut dementia risk by 16%, study of 120,000 finds

A research team from the Department of Pharmacology and Pharmacy, LKS Faculty of Medicine of the University of Hong Kong (HKUMed), has found that nitrogen-containing bisphosphonates (NBPs), a medication widely used in the treatment of osteoporosis, may significantly reduce the risk of Alzheimer's disease and related dementias (ADRD) in older adults with osteoporosis or fragility fractures. This drug repurposing approach offers a promising avenue for the prevention of ADRD, potentially alleviating the global burden of these conditions. The research findings are published in Alzheimer's & Dementia.