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  "path": "/news/2026-03-links-brain-regions-efficacy-antidepressants.html",
  "publishedAt": "2026-03-15T10:00:06.000Z",
  "site": "https://medicalxpress.com",
  "textContent": "Major depressive disorder (MDD) is a severe form of depression characterized by a persistent low mood, hopelessness, disruptions in sleep and/or eating habits, as well as a loss of motivation and interest in daily activities. While there are several treatments for MDD, determining what medications work well for individual patients is often a tiring and challenging trial-and-error process.",
  "title": "Links between brain regions could predict the efficacy of antidepressants"
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