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  "path": "/news/2026-03-uncovering-key-pathway-linking-liver.html",
  "publishedAt": "2026-03-13T10:20:06.000Z",
  "site": "https://medicalxpress.com",
  "textContent": "New molecular insights into the link between hepatocellular carcinoma and intratumoral fibrosis could lead to better treatment strategies, report researchers from Institute of Science Tokyo. Through a comprehensive analysis involving clinical data and in vitro and in vivo experiments, they revealed that the SPP1–CD44–Hedgehog signaling pathway is a key driver of fibrosis in liver tumors, hinting at its potential as a therapeutic target.",
  "title": "Uncovering a key signaling pathway linking liver cancer and fibrosis"
}