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  "path": "/news/2026-03-immune-cells-brain-tune-fertility.html",
  "publishedAt": "2026-03-12T14:00:01.000Z",
  "site": "https://medicalxpress.com",
  "textContent": "The kick-off signal for puberty begins in the brain. Specifically, in the hypothalamus, where specific neurons release a hormone that activates the hypophysis, at the base of the skull, which then releases other hormones to start gonad—ovaries or testicles—maturation. This mechanism leading to a fertile organism is the hypothalamic-pituitary-gonadal (HPG) axis.",
  "title": "Immune cells in the brain may tune fertility hormones, animal study suggests"
}