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  "path": "/news/2026-03-pv-inhibitory-neurons-prefrontal-cortex.html",
  "publishedAt": "2026-03-10T14:40:01.000Z",
  "site": "https://medicalxpress.com",
  "textContent": "Drug addiction carries an extremely high risk of relapse, as cravings can be reignited by minor stimuli even long after one has stopped using. Previously, this phenomenon was attributed to a decline in the function of the prefrontal cortex (PFC), which regulates impulses. However, a joint international research team has recently revealed that the cause of addiction relapse is not a simple decline in brain function, but rather an imbalance in specific neural circuits.",
  "title": "PV inhibitory neurons, not overall prefrontal cortex decline, linked to cocaine-seeking relapse"
}