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  "path": "/news/2026-03-foxj3-gene-emerges-potential-driver.html",
  "publishedAt": "2026-03-09T07:00:02.000Z",
  "site": "https://medicalxpress.com",
  "textContent": "Researchers have discovered that mutations in the FOXJ3 gene act as a \"master switch\" failure, disrupting how the brain builds its layers and leading to FCD, a primary cause of drug-resistant epilepsy. The study, published in Nature Communications, reveals how FOXJ3 controls the formation of brain cortical layers during brain development by regulating the PTEN–mTOR signaling pathway.",
  "title": "FOXJ3 gene emerges as a potential driver of drug-resistant focal epilepsy"
}