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  "path": "/news/2026-02-rett-syndrome-leaky-brain-blood.html",
  "publishedAt": "2026-02-25T16:40:03.000Z",
  "site": "https://medicalxpress.com",
  "tags": [
    "Neuroscience"
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  "textContent": "MIT researchers have discovered that two common genetic mutations that cause Rett syndrome each set off a molecular chain of events that compromises the structural integrity of developing brain blood vessels, making them leaky. The study traces the problem to overexpression of a particular microRNA (miRNA-126-3p), and shows that tamping down the miRNA's levels helps to rescue the vascular defect.",
  "title": "In Rett syndrome, leaky brain blood vessels traced to microRNA"
}