Seven-day buprenorphine injection matches daily tablets for ED opioid treatment

More than 15 years ago, Yale's Gail D'Onofrio started studying the effectiveness of sublingual (under-the-tongue) buprenorphine for treatment of opioid use disorder (OUD) in the emergency department. At the time, buprenorphine was already being used in primary care populations at Yale by David Fiellin, so D'Onofrio and Fiellin decided to test if and how it could work for patients in the ED.