Genetic link to Barrett's esophagus discovered, offering new hope for esophageal cancer patients

Case Western Reserve University researchers have made a significant breakthrough in understanding Barrett's esophagus, a precancerous condition that dramatically increases the risk of developing esophageal adenocarcinoma, one of the fastest-spreading and deadliest forms of cancer. In a new study, they've discovered how inherited genetic abnormalities increase the chance of developing Barrett's esophagus by weakening the esophageal lining, making it more susceptible to harm caused by stomach bile acid.