Decades of drinking reshape gene expression in key human brain regions, study shows

Chronic alcohol consumption profoundly alters gene expression in key brain regions involved in reward, impulse control, and decision-making, according to a study led by researchers at the Institute for Neurosciences, a joint center of Miguel Hernández University of Elche (UMH) and the Spanish National Research Council (CSIC). Published in the journal Addiction, the work provides new insight into the biological basis of alcohol addiction and points toward potential therapeutic targets.