Method of operating an internal combustion engine and corresponding arrangement

A method of operating an internal combustion engine specified to be run with a fuel gas mixture comprising at least one hydrocarbon and hydrogen in a maximum specified hydrogen content using a pipeline gas withdrawn from a pipeline and comprising the at least one hydrocarbon and a hydrogen content exceeding the maximum specified hydrogen content is provided. The pipeline gas is at least in part subjected to a hydrogen depletion to yield a hydrogen depleted gas mixture not exceeding the maximum specified hydrogen content. Said hydrogen depleted gas mixture is at least in part used as the fuel gas and said hydrogen depletion includes a membrane separation. A corresponding arrangement is also part of the present invention.