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  "path": "/article/weight-loss-drugs-dont-work-for-everyone-heres-why/",
  "publishedAt": "2026-06-25T10:00:00.000Z",
  "site": "https://www.scientificamerican.com",
  "textContent": "Some people who take GLP-1 drugs such as semaglutide and tirzepatide see little to no changes to their weight. The reason why may be genetics",
  "title": "Weight loss drugs don't work for everyone—here’s why"
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