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  "path": "/disease/obesity/plateau-weight-loss-mechanism/",
  "publishedAt": "2026-05-27T23:53:57.000Z",
  "site": "https://refractor.io",
  "tags": [
    "Continue Reading",
    "Obesity",
    "Illnesses and conditions",
    "Body and Mind",
    "National Institutes of Health (NIH)",
    "U.S. National Institutes of Health (NIH)",
    "Weight Loss",
    "neurons",
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  "textContent": "Scientists have identified a new way to supercharge the GLP-1 receptor agonist semaglutide, opening the door to boosting the drug's weight-loss power and helping long-term users push past plateaus that not even this \"wonder drug\" can circumvent.\n\nContinue Reading\n\n**Category:** Obesity, Illnesses and conditions, Body and Mind\n\n**Tags:** National Institutes of Health (NIH), U.S. National Institutes of Health (NIH), Obesity, Weight Loss, neurons, Cells, molecular biology, GLP-1 receptor agonists",
  "title": "Brain-cell breakthrough supercharges GLP-1 weight loss and prevents plateaus"
}